Get tanky Drain Hope talents, never lose a 1v1 until lvl 20 and by then you can pretty much 1v5 the enemy team. The more people you hit with your ultimate the better ofc, but the amount of damage you will be able to soak is incredible if you hit 3+ heroes with even one of your swings at lvl 20.

OBS: This is just the build I'm using right now, I am aware that the Ominous Wrath talent at lvl 13 is great for reducing the damage your enemy does to your teammtes but i consider that a much better talent to have when you are not the solo tank of the team.